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Pictet-Spengler condensations using 4-(2-aminoethyl)coumarins.
Sviripa VM, Fiandalo MV, Begley KL, Wyrebek P, Kril LM, Balia AG, Parkin SR, Subramanian V, Chen X, Williams AH, Zhan CG, Liu C, Mohler JL, Watt DS. Sviripa VM, et al. Among authors: kril lm. New J Chem. 2020 Aug 21;44(31):13415-13429. doi: 10.1039/d0nj02664f. Epub 2020 Jul 22. New J Chem. 2020. PMID: 33795928 Free PMC article.
Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents.
Hammill JT, Sviripa VM, Kril LM, Ortiz D, Fargo CM, Kim HS, Chen Y, Rector J, Rice AL, Domagalska MA, Begley KL, Liu C, Rangnekar VM, Dujardin JC, Watt DS, Landfear SM, Guy RK. Hammill JT, et al. Among authors: kril lm. J Med Chem. 2021 Aug 26;64(16):12152-12162. doi: 10.1021/acs.jmedchem.1c00813. Epub 2021 Aug 6. J Med Chem. 2021. PMID: 34355566 Free PMC article.
A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer.
Bi F, Jiang Z, Park W, Hartwich TMP, Ge Z, Chong KY, Yang K, Morrison MJ, Kim D, Kim J, Zhang W, Kril LM, Watt DS, Liu C, Yang-Hartwich Y. Bi F, et al. Among authors: kril lm. Mol Cancer Ther. 2021 Dec;20(12):2398-2409. doi: 10.1158/1535-7163.MCT-21-0396. Epub 2021 Oct 8. Mol Cancer Ther. 2021. PMID: 34625503 Free PMC article.
An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors.
Zhang W, Sviripa VM, Kril LM, Yu T, Xie Y, Hubbard WB, Sullivan PG, Chen X, Zhan CG, Yang-Hartwich Y, Evers BM, Spear BT, Gedaly R, Watt DS, Liu C. Zhang W, et al. Among authors: kril lm. J Med Chem. 2019 Dec 26;62(24):11348-11358. doi: 10.1021/acs.jmedchem.9b01685. Epub 2019 Dec 16. J Med Chem. 2019. PMID: 31774672 Free PMC article.
Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish.
Xie Y, Kril LM, Yu T, Zhang W, Frasinyuk MS, Bondarenko SP, Kondratyuk KM, Hausman E, Martin ZM, Wyrebek PP, Liu X, Deaciuc A, Dwoskin LP, Chen J, Zhu H, Zhan CG, Sviripa VM, Blackburn J, Watt DS, Liu C. Xie Y, et al. Among authors: kril lm. Sci Rep. 2019 Apr 23;9(1):6439. doi: 10.1038/s41598-019-42917-0. Sci Rep. 2019. PMID: 31015569 Free PMC article.
12 results